Basics of NMR
Nuclear Magnetic Resonance spectroscopy (NMR)
NMR is an analytical technique based on the magnetic resonance phenomenon of nuclei that have a spin number I other than zero. The most commonly used nuclei in NMR are: 1H; 13C ; 19F; 31P. This technique requires an intense B0 magnetic field.
For specific applications, the NMR of other nuclei has also been developed, for example the NMR of the 2H; 29Si; 14N; 11B and 10B, 23Na, 17O….and many more.
Some experiments on samples in solution:
- Structural characterization of small organic molecules and proteins
- Study of mixtures (e.g. composition, dosage)
- Determination of equilibrium constants (slow and fast exchange, chemical exchange and conformational exchange, etc.)
- Kinetic studies (rate constant, reaction monitoring, etc.)
Some experiments on solid samples:
- Characterization of inorganic solid materials
- Characterization of gel-type polymers (monitoring of solid-phase reactions)