PURITY CALCULATIONS


Experimentally, the volume out of the burette is: 5.95 mL

Calculation of the purity of raw material:
 
formula for purity calculation
N.A.:
numerical application: mass exp. lido. chlorh. = 31.6 mg
% purity raw material chlorhy. lidocaine = 94.9
However, according to the pharmacopoeia, the content of the raw material must be between 99.0 and 101.0% (desiccated substance). This batch would therefore be discarded in the pharmaceutical industry. It should also be pointed out that the manual handling error in practical tutorials is much higher than in the pharmaceutical industry. Keep in mind nonetheless that this titration is not the one recommended by the pharmacopoeia for this active ingredient.
 
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