TITRATION OF LIDOCAINE HYDROCHLORIDE
Lidocaine hydrochloride: 2(diethylamino)-N-(2,6-dimethylphenyl)acetamide
Local anesthetic, antiarrhythmic (IB class)
Physicochemical data:
CAS number: 73-78-9
Molecular Mass: 288.8 g.mol-1
White crystals. mp 74-79°. Highly soluble in water and alcohol. Soluble in chloroform. Practically insoluble in ether. pH = 4.0-5.5 aqueous solution at 0.5% pKa = 7.9 (25°C)
Maximum absorption: uv max at acid pH: 263 nm (E1%(1cm) = 19); 272 nm.