Choosing and developing an extraction method

How does it work?


To extract compounds of interest, you need to find experimental conditions that favor certain intermolecular interactions and avoid others.

The choice of extractant is therefore crucial: it must allow for the solubilization of the compounds to be extracted, while interacting with the matrix to break solute-matrix interactions; however, the extractant should have very little or no interaction with the interfering compounds present (see illustrative diagram).

Diagram illustrating the interactions. 4 elements are present: the matrix, the solute, the extractant and the interfering compounds. Some interactions are to be favored: extractant - matrix, extractant - solute and interfering compounds - matrix. Other interactions are to be avoided: solute - matrix and interfering compounds - extractant.
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