Pressurized Liquid Extraction (PLE)

Pressurized liquid extraction (PLE) is an extraction technique dedicated to solid matrices (also called pressurized hot solvent extraction –PSE, or accelerated solvent extraction - ASE).

It is based on a simple principle: a solid sample is extracted by a highly heated solvent (or mix of solvents) so as to accelerate the extraction process. As the solvent has to be maintained in its liquid state, the extraction is performed under pressure. It is conducted in several successive steps (see diagram).