HOW TO CALCULATE THE PURITY OF THE RAW MATERIAL OF AN ACTIVE INGREDIENT

Calculation for paracetamol:
  • Raw material 10mg/mL
  • Lindilane® 10 mg/mL
The calibration line gives experimental values for both raw material (RM) and galenic form (GF) concentrations.

[RM] = 9.86 mg/L
[GF] = 7.97 mg/L
 
1) Calculation of raw material purity:
Experimental value is 9.86mg/L instead of the theoretical 10 mg/L.

Purity of the raw material is therefore 98.6%.

This batch does not comply with the range provided by the pharmacopoeia (99-101%), but is still acceptable given the equipment used in practical tutorials.
 
Photo of a photometry result, showing the result table and the calibration line
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