Basics of GC

A few questions


Which compounds can be separated by gas chromatography?


Volatile or volatilizable compounds can be analysed: permanent gases, volatile solvents, aromas, and generally compounds with a molecular mass lower than 400 g/mole


What is the advantage of the split injection mode (division mode)?


It preserves the chromatographic resolution and avoids saturation phenomena.


How to choose the nature of the stationary phase adapted to the separation?


The stationary phase must be adapted to the polarity of the solutes to be separated.


How are the column dimensions chosen?


The choice of the column geometry depends on: the volatility of the solutes, the analysis time, and the complexity of the mixture to be separated.


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