The first step is to insert the tip adapted to the chosen micropipette and to the sample to be taken.

There are many different types of tips: some come with a filter to prevent contamination or pipette damage when sampling a corrosive liquid; others are extended for sampling in long tubes, or have extra thin tips for depositing in electrophoresis gel wells; others are in treated special plastic to limit retention, and so on.

The tip should be loaded onto the micropipette without forcing it. A rotational movement is preferable, if necessary.

Never use the micropipette as a hammer!
Use a rotational movement instead for pushing
the tip into the cone.